Patients usually take hytrin at bedtime for the first 4 nights to reduce the chances of dizziness.
Caution should be observed when terazosin is administered with other antihypertensive agentsto avoid the possibility of significant hypotensionWhen adding terazosin to a diuretic or other antihypertensive agentdosage reduction and retitration may be necessary.
Hytrinterazosin hydrochloridean alpha-1-selective adrenoceptor blocking agentis a quinazoline derivative represented by the following chemical name and structural formula:
In in-vitro experimentsterazosin has been shown to antagonise phenylephrine-induced contractions of human pro static tissueIn clinical trials terazosin has been shown to improve the urodynamics and symptomatology in patients with BPH.
Weight increasedDecreased haematocritdecreased haemoglobindecreased white blood cell countdecreased total protein and decreased blood albuminsuggestive of haemodilution)
In patients receiving terazosin plus ACE inhibitors or diuretics the proportion reporting dizziness or related side effects was greater than in the total population of terazosin treated patients from clinical trials.
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